基因检测与肝保养


癌王不是浪得虚名
肝癌,一般指生长于肝细胞或肝内小胆管上皮细胞的恶性肿瘤,包括原发性肝癌和转移性肝癌两种,提起肝癌通常指的是原发性肝癌。如果把与肝相关的疾病列一个分级,那么肝炎算是个初级体,肝硬化是升级体,而究极体——被称为肝癌,就是大家口中的那个“癌症之王”。由于肝癌起病隐匿,平期不易引起患者重视,导致发现时多数已属晚期,非常容易错过最佳的治疗时间。
根据统计,肝癌是病死率最高的恶性肿瘤之一。[1]我国每年约有38.3万人死于肝癌,占全球肝癌死亡病例数的51%,全世界每年新发肝癌患者约60万,肝癌死亡率在全球癌症死亡率中排名第二位。原发性肝癌多高发于非洲东南部和东南亚,我国多见于东南沿海地带,例如江苏、福建、广东、广西等,而且尤其在成年男性群体中高发,发病年龄趋于年轻化。
肝癌也有前因后果
经研究表明,中国肝癌的发生与诸多因素相关,主要可以区分为以下几类:
病毒感染:已知的肝炎病毒至少有A,B,C,D,E,G等类型,病毒性肝炎与肝癌关系主要为乙型肝炎与丙型肝炎即HBV和HCV。肝癌患者中约有1/3的病人有慢性肝炎史,澳抗阳性率明显高于低发区,已发现丙型肝炎病毒感染和乙型的感染一样,与肝癌发病有密切的关系,乙肝肝炎病毒和丙型肝炎病毒是促癌因素之一。
黄曲霉素:动物实验证明,黄曲霉素的代谢产物B1有强烈的致癌作用,存在于霉变的玉米,花生等食品中,食品被黄曲霉毒素B1污染严重的地区,肝癌的发病率也较高。亚硝胺类、偶氮芥类、酒精、有机氯农药等均是可疑的致癌物质。
饮水污染:一些饮用水常被多氯联苯、氯仿等污染,近年来发现池塘中生长的蓝绿藻是强烈的致癌植物,可污染水源。寄生虫病如华支睾吸虫感染可刺激胆管上皮增生,也可导致原发性胆管癌。
消极情绪及精神压力:现代人生活节奏较快,生活压力大,长期以往产生的负面情绪会对肝脏带来程度不定的压力,也被认为是现代人患肝癌的隐患之一。
遗传因素导致肝癌:肝癌具有明显的家族聚集性和遗传易感性。在有肝癌病例的家族中,其亲人出现肝癌的风险远高于无血缘关系的常人。环境的改变和病毒的作用都可引发基因突变,造成肝细胞异常分裂发生癌变。
说到底早防早治才是关键
◆ 预防肝炎,注射肝炎疫苗预防肝炎发生。
◆ 注意任何可能传播乙肝病毒的途径,如手术、输血、针灸及理发等,不与乙肝患者共用餐具。
◆ 尽早戒烟限酒,不喝烈性酒。
◆ 多吃新鲜蔬果,多运动,不吃发霉、烧糊及烧烤、油炸、腌制等食物。
◆ 要注意饮水卫生,尤其是不能喝含有毒化学物质的水,有条件者可将自来水二次过滤消毒后再饮用。
◆ 肝癌高危人群要主动、积极地进行相关筛查,预防及远离肝癌发生。
爱肝护肝,保护你的小心肝
1、保证充足的睡眠和规律饮食
长期熬夜会导致肝脏供养不足,进而使肝脏细胞的修复率降低。充足的睡眠是养护肝脏的重要保障,晚上11点到凌晨3点尤其重要,保证睡眠将肝脏的损害降到最低。
春季养肝护肝,饮食上要以清淡为主,可以多吃芹菜、莴笋、豆芽等新鲜蔬菜,避免食用辛辣食物。可以食用大豆或豆腐等含有丰富蛋白质、钙、铁、磷等的食物,帮助提高免疫力,保证肝脏健康。
2、生气勿超3分钟
中医讲“肝主情志”,肝异常会影响人的情绪;反之,心情的好坏也会影响到肝。所以,保持一个良好的心情是养肝血的一个好方法。当情绪不舒畅时,尽量能够找一个可以诉说的人,或找一种可以发泄心中郁闷的方式来疏泄这种坏的情绪,不要硬憋在心里。据相关数据,癌症和一些肿瘤患者中,无法疏泄心中郁闷的是其他人群的2~4倍。所以,老百姓常说:“万病气上来。”
遇到不痛快的事,肝气郁结难受时,可以尝试“嘘肝法”:面对常青绿色树木,口发“嘘”的声音,缓缓地、深深地吐出一口恶气,一直到心情好转为止。经常伏案工作的白领一族,可以在自己的电脑旁边摆一盆常青植物盆景,如芦荟等,可以养眼舒肝。
3、适当地按摩穴位
肝脏主理疏泄与藏血。而春季易出现肝火旺盛的症状,建议可以按摩太冲穴。太冲穴堪称人体第一大要穴,是肝经的火穴,能够把肝气肝火消散掉。每天抽出几分钟时间按揉太冲穴,能够调动肝经的元气,起到补阴、养肝、柔肝的作用。

随着现代生活发展,人们对于健康的重视程度越来越高。而疾病,是威胁健康的最大祸首。
相信有的人为了健康会选择进行常规体检,但是你有没有发现身边不乏有平时看起来很健康,非常突然就检出重疾的人。常规体检一检即知的结果,无疑给受检者当头一棒,再想挽回已无济于事…….难道健康与疾病只有一线之隔吗?我们都知道冰冻一尺非一日之寒的道理,疾病更是如此……那么,如何尽早知晓疾病发生风险,在疾病发生之前就觉察到疾病的存在呢?
体检新模式:基因+体检
什么是基因体检?
我们都知道疾病的成因复杂,有的疾病在人一出生时就带有特定的遗传特征,或者说携带某种疾病的易感基因组型。基因检测,是通过对个体遗传的角度分析对某种疾病的易感性。通俗来说就是从基因的角度评估一个健康人未来患某种疾病的可能性高低,探察由遗传决定的易患某种或某类疾病的倾向,并有针对性地给出健康管理的方案,避免或延缓疾病的发生。
基因体检适合人群?
基因(遗传因子)是遗传变异的主要物质。基因支持着生命的基本构造和性能。储存着生命的种族、血型、孕育、生长、凋亡过程的全部信息。生物体的生、长、老、病、死等一切生命现象都与基因有关。基因是决定生命健康的内在因素,因此全人群都适合做基因检测。
基因体检有何意义?
大家可能都听说过:好莱坞当红女星安吉丽娜.朱莉证实依据自身癌症基因预测罹患乳腺癌和卵巢癌的风险很高,决定接受预防性双乳切除手术以降低罹癌风险。事实上很多癌症都可以通过基因检测来预测其发生的可能性,采取一定的手段进行干预,减少该疾病的发病风险。
基因体检的意义就在于可以预知自己身体健康的短板,提前进行预防,通过更合理的生活方式和个性化的体检方案,对身体短板有更精准的掌控。
检测出高风险怎么办?
基因检测结果提示高风险,意味着受检者本人的相关患病风险与正常人群相比会有不同程度的增加,但并不意味着受检者一定会患病。疾病的发生是遗传因素和环境因素共同作用的结果,携带有易感基因的个体可以通过避免疾病相关诱因、健康的生活方式和相应的医疗预防措施来降低患病风险,避免疾病的发生。
体检有区别
基因体检——疾病的零级预防
检测基因,在疾病发生前,预测将来患病的风险,降低疾病发生概率
检测目的:遗传风险筛查
检测技术:二代测序
检测频次:一次检测,终身受益
常规体检——疾病的即时诊断
常规体检检测当下的身体状况,预警已有的疾病征兆,辅助疾病诊断
检测目的:诊断依据
检测技术:CT,B超,X光,病理化验等
检测频次:至少一年一次,定期检测
健康全方位
基因体检与常规体检在疾病防治方面互为补充,个体的健康管理两者缺一不可。譬如,某人心脏有问题,如果能够在5-10年前利用基因检测获知心脏疾病存在着中高风险,就可以适当减少剧烈运动,调整饮食及生活方式,指导受检者在未来的健康体检中侧重加强与心脏疾病相关的筛查及指标检查,最大程度远离疾病困扰。
基因体检—优福集因
优福联合亚洲一流的医学基因组中心——安诺优达,引进美国Illumina二代高通量测序技术及高性能计算平台,提供科学全面的330+项基因检测服务。从遗传角度认识自身遗传特质中存在的健康风险因素和个人特征,提供个性化保健、个性化预防、个性化营养与膳食、个性化体检、个性化用药等健康指导建议,帮助受检者建立科学合理的生活方式,提供个性化健康指导,让您提前采取措施进行针对性防治,降低疾病的发生风险。
人为什么会生病?
除了先天的易感基因遗传病变外,就是后天的免疫力下降致病了。免疫力,是机体自身的免疫能力,是人体抵抗外界疾病侵袭的能力。
现代人却很少注意自己的免疫力,很多人都认为只有孩子才需要提高免疫力,自已身强体壮的,疾病早就找不上自己的。其实我们的身体都会受到疾病的侵袭,当你的身体出现以下的这些症状时就说明你的免疫力下降了,需要提高自身的免疫力了。
免疫力低下的表现
一、感冒不断而且反复发作
天气稍有变化无论是变冷还是变热,不及时加减衣服就会开始打喷嚏,然后感冒便时时相伴,成了你的家常便饭,而且要经历好长一段时间才好。感冒反复发作,这就说明你的免疫力有所下降。
二、特别容易感到疲劳
工作中没精神,提不起劲,稍微多做一点事就觉得累了,去医院检查却检查不出什么器质病变,休息一段时间后你的精力又缓解,可这样又持续不了几天,疲劳感又出现了。
三、肠胃娇气爱生病
如果在外面吃饭,别人都安然无恙,只有你却上吐下泻,这说明你的肠胃的自身保护功能存在问题,这也是免疫力低的一种表现。
四、自身伤口容易感染
当你的同事或家人感冒时,你也总是被传染,那就说明你总是被传染病所伤害,这时证明你的抵抗力存在问题了。自己的身体哪个部位不小心被划伤的时候,正常人几天就可以好,而你却总是伤口红肿流脓,要很长时间才能好,也说明抵抗力下降。
天天加班、熬夜,经常头晕、出虚汗?
经常腹泻、疲劳、精神差、易感冒?
五十岁前以身体换钱,五十岁后以钱换身体。人生下半场最输不起的是时间,拼的是健康。
对待我们的身体健康,就好比中国环境保护,你也在走着“先污染后治理”的老路吗?除了远离化学污染,改变生活习惯外,就是要调理养生,提高身体免疫力,预防疾病,规避易感基因患病风险。
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Today, I went to the beach with my children. I found a sea shell and gave it
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★肝病表现与体验指标★
肝脏出现健康问题的话,可就不是小病小痛了,无论是肝炎还是肝硬化,甚至发展成为肝癌,都有可能威胁到生命的,所以如果感觉自己的生活习惯不好,特别是感觉到自己经常出现口干口苦、身体消瘦亦或是胸口时常不舒服的人,最好都要去医院检查一次肝脏的健康情况。
肝脏的体检从来不会是多此一举的,与其到了病入膏肓的时候才被确诊,不如防范于未然地做体检,那么对于肝脏的检查,从体检报告上有哪些指标是重点解读对象呢?
一、转氨酶升高,是肝脏受损的信号
大家都知道,肝脏是我们人体的代谢中心,摄入的食物很多会在肝脏进行代谢,也就是通过一系列的反应和作用生成人体需要的物质,不需要的物质则会通过排泄作用排出体外,那么在这一系列的反应过程中就需要用到各种酶,尤其是转氨酶,比如天冬氨酸转氨酶、丙氨酸氨基转氨酶等等,但是,在正常情况下,这些转氨酶都是处于肝脏细胞内部参与相关的反应。如果在体检时发现转氨酶含量升高,那就说明肝脏受损了,比如肝细胞出现不完整的情况,使得转氨酶渗入血液中,造成含量升高的情况。
二、高浓度的胆红素,意味着肝脏出现异常
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